P2.3 Haemophilus influenzae immunisation

A Cochrane Review/meta-analysis of six placebo-controlled RCTs evaluating 557 patients, conducted to test the efficacy of enteric-coated, killed preparations of H. influenzae in populations prone to recurrent exacerbations of chronic bronchitis or COPD, concluded that there was no significant reduction in exacerbations in the vaccinated group when compared to the placebo group (Teo 2017).