P2. Immunisations P2.1 Influenza immunisation Influenza immunisation reduces the risk of exacerbations, hospitalisation and death (Nichol 1994, Poole 2006) [evidence level I]. Annual influenza immunisation reduces by about 50% the…
…and 34 control participants, demonstrating clinically significant improvements in SGRQ of -10.6 (95%CI -15.9 to -5.4) and improvement in FEVâ‚ +10.3% predicted (95% CI 4.7-16.0) in the coil arm. There…
…(HR 1.14, 95% CI 1.00–1.29; p=0.04). Opioid use was also associated with significantly increased risk for COPD or pneumonia-related mortality (HR 2.16, 95% CI 1.61–2.88) and all-cause mortality (HR 1.76,…
…10-66 [evidence level I], the duration of ventilatory assistance (mean difference of -2.05 days, 95% CI -2.60 to -1.51 compared to control, data from 2 studies of 54 patients) [evidence…
…CI 0·85–1·02;p=0·0498) and time to first moderate or severe event ([HR] 0·95, 99% CI 0·87–1·03; p=0·12) over a 52-week treatment period compared to tiotropium alone (Calverley 2018b) [evidence level II]….
…ratio 0.67, 95% credible interval 0.60 –0.75) compared to placebo and improving quality of life (mean difference in SGRQ of -2.30, 95% credible interval -3.61 to -0.99, although this difference…
…days, then 150 mg twice daily (at least eight hours apart) for between seven and nine weeks, in combination with counselling. A quit date should be set (e.g. Day 5–10)….
…2012). Higher prevalence of cardiac disease, stroke, diabetes, depression, poly-pharmacy and mobility problems were reported. The concept of multimorbidity has been increasingly discussed in primary care. Multimorbidity refers to co-occurrence…
…diagnosis and refer for pharmacological and non-pharmacological management FEV1, forced expiratory volume in 1s; COPD, chronic obstructive pulmonary disease. Box adapted from British Thoracic Society Statement (British Thoracic Society 2008b)….
…used the evidence ranking system of the US National Heart, Lung and Blood Institute (NHLBI) (NHLBI/WHO Workshop Report April 2001). The NHLBI scheme is shown in Box 1. For comparison,…